Leveraging wastewater sequencing to strengthen global public health surveillance

GORDEEV, Victor; HÖLZER, Martin; DESIRÒ, Daniel; GORAICHUK, Iryna V.; KNYAZEV, Sergey; SOLO‑GABRIELE, Helena; SKUMS, Pavel; KARTHIKEYAN, Smruthi; EVANS, Alexandria; AGRAWAL, Shelesh; LUCACI, Alexander G.; MASON, Christopher E.; SU, Justin M.; GIBAS, Cynthia; NAGARAJAN, Niranjan; PERES da SILVA, Rafael; DRABCINSKI, Nicolae; MUNTEANU, Viorel; ZHAN, Lingyu; RUBIN, Julia; WU, Nicholas C.; TRISTER, Andrew; CIORBA, Dumitru; BOSTAN, Viorel; LOBIUC, Andrei; COVASA, Mihai; OPHOFF, Roel A.; ZELIKOVSKY, Alex; DIMIAN, Mihai; MANGUL, Serghei

Leveraging wastewater sequencing to strengthen global public health surveillance

GORDEEV, Victor; HÖLZER, Martin; DESIRÒ, Daniel; GORAICHUK, Iryna V.; KNYAZEV, Sergey; SOLO‑GABRIELE, Helena; SKUMS, Pavel; KARTHIKEYAN, Smruthi; EVANS, Alexandria; AGRAWAL, Shelesh; LUCACI, Alexander G.; MASON, Christopher E.; SU, Justin M.; GIBAS, Cynthia; NAGARAJAN, Niranjan; PERES da SILVA, Rafael; DRABCINSKI, Nicolae; MUNTEANU, Viorel; ZHAN, Lingyu; RUBIN, Julia; WU, Nicholas C.; TRISTER, Andrew; CIORBA, Dumitru; BOSTAN, Viorel; LOBIUC, Andrei; COVASA, Mihai; OPHOFF, Roel A.; ZELIKOVSKY, Alex; DIMIAN, Mihai; MANGUL, Serghei

URI: https://doi.org/10.1186/s44263-025-00138-w
https://repository.utm.md/handle/5014/35731

Date: 2025

Abstract:

Sequencing-based wastewater surveillance offers a scalable and cost-effective approach for monitoring pathogens circulating within communities. We explore innovations and necessary actions, calling for standardized procedures for sample collection, processing, and sequencing, improved pathogen enrichment and targeted sequencing methods, and dedicated bioinformatics tools and databases to strengthen wastewater-based pathogen surveillance.