Evaluation of the Quercetin Semisynthetic Derivatives Interaction with ABCG2 and Cyclooxygenase-2

MANUKYAN, A. E.

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dc.contributor.author	MANUKYAN, A. E.
dc.date.accessioned	2020-05-29T08:52:31Z
dc.date.available	2020-05-29T08:52:31Z
dc.date.issued	2019
dc.identifier.citation	MANUKYAN, A. E. Evaluation of the Quercetin Semisynthetic Derivatives Interaction with ABCG2 and Cyclooxygenase-2. In: ICNMBE: International conference on Nanotechnologies and Biomedical Engineering: proc. of the 4rd intern. conf., Sept. 18-21 : Program & Abstract Book , 2019. Chişinău, 2019, p. 131. ISBN 978-9975-72-392-3.	en_US
dc.identifier.isbn	978-9975-72-392-3
dc.identifier.uri	https://doi.org/10.1007/978-3-030-31866-6_98
dc.identifier.uri	http://repository.utm.md/handle/5014/8448
dc.description	Access full text - https://doi.org/10.1007/978-3-030-31866-6_98	en_US
dc.description.abstract	Cancer multiple drug resistance and the inflammatory process are the main problems for successful chemotherapy. In anticancer therapy, plant and semisynthetic compounds are considered as potential modifiers for ABCG2 and COX2 inhibitors. As a result of experiments carried out in silico, the possible interaction of ABCG2 and inhibition of COX-2 by semisynthetic derivatives of quercetin were first revealed. The physicochemical parameters of the studied lig- ands were revealed, after which, for reliability, they were compared with in vitro experiments.	en_US
dc.language.iso	en	en_US
dc.publisher	Tehnica UTM	en_US
dc.rights	Attribution-NonCommercial-NoDerivs 3.0 United States	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject	quercetin derivatives	en_US
dc.subject	anticancer therapy	en_US
dc.title	Evaluation of the Quercetin Semisynthetic Derivatives Interaction with ABCG2 and Cyclooxygenase-2	en_US
dc.type	Article	en_US