Synthesis and characterization of copolymers based on styrene-butadiene grafted with antimicrobial agents

Abstract

The paper describes polymer materials based on styrene–butadiene grafted with antimicrobial components. The engraftment of copolymer styrene: butadiene-1,2 with methacrylic acid has been performed. The structure of grafted copolymer was confirmed by IR spectroscopy and by elemental analysis. It has been demonstrated that a rest of methacrylic acid joins the vinyl compound. Through an analogue polymer-transformation we succeeded in coupling of antimicrobial compounds such as ampicillin and others to ST:BD copolymer grafted with methacrylic acid. The structure of medicinal copolymer as well as the content of ampicillin has been confirmed by IR spectroscopy and elemental analysis. It has been shown that 65-70% COOH groups were subjected to transformation. Antimicrobial tests of medicinal copolymer demonstrated almost an identical activity of standard copolymer N-vinylpyrrolidone with metacrilic acid. The developed medicinal copolymer can be recommended or use in manufacturing of household items as well as of items of furniture, or part of the clinical household utensils having the possibility to improve the hygienic indices.