Efficacy and safety of the video-observed treatment in patients with pulmonary tuberculosis

Abstract

The aim was to assess the efficacy and safety of the video-observed treatment (VOT) in patients with pulmonary TB. A prospective case-control study included 114 patients with PTB treated with VOT, distributed in the group 1 (G1) - 26 cases treated in both therapeutic phases using the VOT and the group 2 (G2) - 88 cases treated by VOT only in the continuation phase in the period 2019-2022 in Chisinau was conducted. Therapeutic success was established in 24 (92%) vs 78 (89%) cases, died 1 (2%) patient as result of the comorbid state and 1 (1.3%) continued the treatment in G1 vs 10 (11%) in G2. Adverse drug reactions were minor, managed remotely and included only gastroientestinal disorders in 3 (11,3%) vs 2 (2,3%).