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Coordination Compounds of Cu(II), Ni(II) Based on Ethyl 4-benzoate Thiosemicarbazons Derivatives of Salicyl Aldehyde. Antimicrobial and Antifungal Properties

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dc.contributor.author RUSNAC, A.
dc.contributor.author BALAN, G.
dc.contributor.author GULEA, A.
dc.date.accessioned 2021-11-15T11:34:51Z
dc.date.available 2021-11-15T11:34:51Z
dc.date.issued 2021
dc.identifier.citation RUSNAC, A., BALAN, G., GULEA, A. Coordination Compounds of Cu(II), Ni(II) Based on Ethyl 4-benzoate Thiosemicarbazons Derivatives of Salicyl Aldehyde. Antimicrobial and Antifungal Properties. In: ICNMBE-2021: the 5th International Conference on Nanotechnologies and Biomedical Engineering, November 3-5, 2021: Program and abstract book. Chişinău, 2021, p. 114. ISBN 978-9975-72-592-7. en_US
dc.identifier.isbn 978-9975-72-592-7
dc.identifier.uri http://repository.utm.md/handle/5014/18054
dc.description Only Abstract. en_US
dc.description.abstract The article publishes in vitro tests of the antibacterial and antifungal properties of new сoordination compounds of Cu(II), Ni(II) based on ethyl 4-benzoate thiosemicarbazons derivatives of salicyl aldehyde. Two Gram-positive strains were taken as reference strains: Staphylococcus aureus ATCC 25923 and Bacillus cereus ATCC 11778; two Gram-negative strains: E.coli ATCC 25922 and Acinetobacter baumannii BAA-747; three fungal strains: Candida albicans ATCC 10231, Candida krusei ATCC 6258, Cryptococcus neoformans CECT 1043. The best results were recorded at {Ni(HL1)Cl} complex, a selectivity is observed on Cryptococcus neoformans, with CMI = 0.016, CMF = 0.031 mg/mL and is twice as active as the control substance Nystatin. The purity and structural formula of synthesized compounds was confirmed by thin layer chromatography; IR spectroscopy; 1H, 13C Nuclear Magnetic Resonance Spectroscopy, metal analysis and magnetochemical analysis. en_US
dc.language.iso en en_US
dc.publisher Universitatea Tehnică a Moldovei en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject compounds of Cu(II), Ni(II) en_US
dc.subject salicyl aldehyde en_US
dc.subject Nuclear Magnetic Resonance Spectroscopy en_US
dc.title Coordination Compounds of Cu(II), Ni(II) Based on Ethyl 4-benzoate Thiosemicarbazons Derivatives of Salicyl Aldehyde. Antimicrobial and Antifungal Properties en_US
dc.type Article en_US


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