Collagen - Isolation and Perspectives of Application of Nature Nanomaterials

Abstract

Through the extreme diversity of tissues and types of collagen it is difficult to develop a standard method of extraction for all types of collagen from different tissues. Two procedures based on acid- and enzymatic-soluble collagen isolation were combined and described some advantages and disadvantages of methods used in the present. Our results have demonstrated relatively low concentrations of collagen in the final solutions. There is 4,7 mg/ml from theoretically 10 mg/ml of acid-soluble fraction of collagen. Here are discussed the possibility to utilize the collagen, as fibrous structural protein with superior mechanical properties, that provides an intriguing example of a hierarchical biological nanomaterialas, for the construction of nanostructures with the required dimensions.