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The use of floating multichannel electrodes for monitoring the electrical activity of the myocardium

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dc.contributor.author VLASENKO, Oksana
dc.contributor.author ROKUNETS, Ihor
dc.contributor.author CHAIKOVSKA, Olga
dc.contributor.author CHECHEL, Viktor
dc.contributor.author SIDORENKO, Ludmila
dc.contributor.author SIDORENKO, Svetlana
dc.contributor.author VLASENKO, Oleg
dc.date.accessioned 2024-04-25T11:51:53Z
dc.date.available 2024-04-25T11:51:53Z
dc.date.issued 2024
dc.identifier.citation VLASENKO, Oksana, ROKUNETS, Ihor, CHAIKOVSKA, Olga et al. The use of floating multichannel electrodes for monitoring the electrical activity of the myocardium. In: Quo Vadis – Ethics of the Scientific Research: conf. NANO-2024, event devoted to the 60th anniversary of the Technical University of Moldova, 15-18 April 2024, Chişinău, Republica Moldova: Program and proceedings of the conference, Chişinău 2024, pp. 76-77. ISBN 978-9975-64-422-8. en_US
dc.identifier.isbn 978-9975-64-422-8
dc.identifier.uri http://repository.utm.md/handle/5014/26920
dc.description.abstract The development of novel drugs necessitates meticulous monitoring of various critical aspects to mitigate the risk of cardiovascular complications. Researchers must consider a plethora of targets ranging from the molecular level of ionic channels to the systemic effects of novel compounds. Employing techniques of different scales, such as electrocardiogram (ECG) recordings and field potential recordings of cardiomyocytes with implanted electrodes, presents a challenging yet rewarding approach. This design can yield comprehensive insights into the state of cardiomyocytes within the heart chambers and the heart as a whole. By conducting measurements under conditions where other organs remain intact, researchers can assess the systemic effects of compounds and anticipate or confirm adverse effects during preclinical research. Moreover, this setup provides an opportunity for additional interventions and the simultaneous monitoring of other parameters in the same animal. en_US
dc.language.iso en en_US
dc.publisher Technical University of Moldova en_US
dc.relation.ispartofseries NANO-2024 "Quo Vadis – Ethics of the Scientific Research", event devoted to the 60th anniversary of the Technical University of Moldova;15-18 April 2024, Chişinău, Republica Moldova
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject electrical activity en_US
dc.subject floating multichannel electrodes en_US
dc.subject cardiomyocytes en_US
dc.subject myocardium en_US
dc.title The use of floating multichannel electrodes for monitoring the electrical activity of the myocardium en_US
dc.type Article en_US


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