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Prevalence of some PIK3CA mutations in patients with cervical Squamous Carcinoma from the Republic of Moldova

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dc.contributor.author POPA, Cristina
dc.contributor.author STRATAN, Valentina
dc.contributor.author TUTUIANU, Valeri
dc.contributor.author SITNIC, Victor
dc.contributor.author BALAN, Veronica
dc.contributor.author NOVAC, Mihail
dc.contributor.author SPRINCEAN, Mariana
dc.contributor.author CASIAN, Neonila
dc.date.accessioned 2024-04-25T07:39:44Z
dc.date.available 2024-04-25T07:39:44Z
dc.date.issued 2024
dc.identifier.citation POPA, Cristina et al. Prevalence of some PIK3CA mutations in patients with cervical Squamous Carcinoma from the Republic of Moldova. In: Quo Vadis – Ethics of the Scientific Research: conf. NANO-2024, event devoted to the 60th anniversary of the Technical University of Moldova, 15-18 April 2024, Chişinău, Republica Moldova: Program and proceedings of the conference, Chişinău 2024, pp. 59-60. ISBN 978-9975-64-422-8. en_US
dc.identifier.isbn 978-9975-64-422-8
dc.identifier.uri http://repository.utm.md/handle/5014/26905
dc.description.abstract The study aimed to determine the prevalence of mutations in the PIK3CA gene in a cohort of CSCC patients from the Republic of Moldova. The tested prevalence of the PIK3CA mutations was 29.35%. Testing revealed that 25 patients were positive for a single mutation, and two tested positive for a double mutation. Since many patients have these mutations, there is a chance that CSCC patients from the Republic of Moldova will benefit from the development of anti-PI3K targeted therapy. en_US
dc.language.iso en en_US
dc.publisher Technical University of Moldova en_US
dc.relation.ispartofseries NANO-2024 "Quo Vadis – Ethics of the Scientific Research", event devoted to the 60th anniversary of the Technical University of Moldova;15-18 April 2024, Chişinău, Republica Moldova
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject cervical squamous cell carcinoma en_US
dc.subject targeted therapy en_US
dc.title Prevalence of some PIK3CA mutations in patients with cervical Squamous Carcinoma from the Republic of Moldova en_US
dc.type Article en_US


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